8 results
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
(Acute Febrile ... inflammatory disease, or pregnancy ... Excellent response to treatment ... rate >20 mm/h; positive ... #Hematology #Dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... , breast CA - Hematologic ... Treatment: - Systemic ... #Syndrome #diagnosis ... #dermatology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... febrile neutrophilic ... Renal Failure Treatment ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
presents as an acute ... or subacute febrile ... • Bicytopenia Treatment ... #management #treatment ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... At least 3 of (Acute ... heart failure, positive ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... organ damage • Treatment ... : - If febrile ... Syndrome #TLS #diagnosis ... #management #hematology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Acute generalized ... pustulosis • Febrile ... Sweet syndrome ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... • Prognosis: Fatal ... search for and treatment ... Treatment Approach ... #Management #Hematology