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diagnosis differential hematology aflp obstetrics comparison hellp hypertension liver management obgyn pathophysiology table thrombocytopenia ttphus workup algorithm anemia antiphospholipid aplastic
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... : • Defect in fetal ... = nonspecific (nausea ... #Liver #Pregnancy ... #hepatology #obstetrics
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute Fatty ... Liver of Pregnancy ... child * Severe cases ... plasma exchange 3) Fatty ... AFLP #obstetrics #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia and Pregnancy ... critically ill pregnant ... child * Severe cases ... plasma exchange 2) Fatty ... Obstetrics #OBGyn #Hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... post-partum • Typical clinical ... hemorrhage Acute Fatty ... Hepatic imaging: Fatty ... #hepatology #obstetrics
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... Post-Hepatic: • Cardiac causes ... metastasis • Fatty ... liver of pregnancy ... #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... - Acute fatty ... liver of pregnancy ... peritonitis #Ascites #Causes ... #differential #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Intravenous Drug Use • Pregnancy ... from prosthetic valves ... Infected cardiac valves ... coagulation and other causes ... pathophysiology #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Causes of Secondary ... previously stable values ... 109 mm Hg) with clinical ... Causes: • Vascular ... Pregnancy-associated
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... Marrow hypoplasia/fatty ... Anemia #oncology #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
- 1 or more clinical ... • Unexplained pregnancy ... maternal chromosomal causes ... Algorithm #diagnosis #hematology
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