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differential management treatment algorithm hepatopulmonary neurology rheumatology anemia bilirubin bilirubinemia cerebritis cirrhosis cns congenital cryofibrinogenemia eosinophilia eosinophils erythematosus extravascular gastroenterology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • ... #Hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
- Differential Diagnosis ... Sepsis • Drugs (e.g ... Post-Hepatic - Usually has ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... nephrotoxics (e.g ... #diagnosis #HRSAKI ... #HRSNAKI #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... (HUS) • Other ... #hematology #anemia
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
not specific to HPS ... detects severe HPS ... minutes of rest HPS ... resolution of HPS ... #treatment #hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... (for secondary APS
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Prevalence: 1-2 cases ... Clinical Manifestations ... - People with SPS ... #SPS #Diagnosis
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... than 1500 and clinical ... eosinophilia Secondary Causes ... #diagnosis #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
• Has a UGT1A1 ... as jaundice on clinical ... and stress may cause ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... : • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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