39 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... aldosteronism • High Al ... #Hypokalemia #Differential ... #causes #low #potassium
MDRO: Multiple Drug Resistant Organism (Stenehjem E et al. Clin Infect Dis. 2016; 63(10): 1273-1280)

#AntibioticClassificationSchema #Antibiotics
Stenehjem E et al ... AntibioticClassificationSchema #Antibiotics ... clinical #management #pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
with excreting potassium ... Antagonists), all ... will increase potassium ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
(PO and IV) - Antibiotics ... Spectrum: covers all ... infections #Pharmacology ... #Antibiotics #Review
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... #hyperkalemia #differential
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Potassium Channel ... Organophosphates #Potassium ... #Medications #Differential ... #Diagnosis #Pharmacology
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
lipoglycopeptide antibiotics ... ) - Antibiotics ... Used for: all sorts ... #Pharmacology #Antibiotics
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... 30S inhibitor (all ... #Pharmacology #Antibiotics