25 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP DIURETICS ... Chlorthalidone POTASSIUM-SPARING ... Tolvaptan #Diuretics ... #Medications #Pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Pharmacology #
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
(PO and IV) - Antibiotics ... Class Overview ... Spectrum: covers all ... infections #Pharmacology ... #Antibiotics #Review
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... pathophysiology #pharmacology ... #potassium #medications
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... 30S inhibitor (all ... #Pharmacology #Antibiotics ... #Review #Overview
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
) - Antibiotics ... Class Overview ... Used for: all sorts ... #Pharmacology #Antibiotics ... #Review #Overview
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Saline or osmotic diuresis ... - Potassium depletion ... Drugs: - Loop diuretics ... #differential #medications ... #drugs #pharmacology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
with excreting potassium ... Antagonists), all ... diuretic, which ... , just like all ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... Anidulafungin #Pharmacology ... #Antibiotics #Review ... #Overview #Echinocandins