16 results
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... , Rheumatoid Vasculitis ... in APL - Cardiac ... Kumfer @AnnKumfer #Pulmonary ... #Renal #Syndromes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... • Rheumatic Diseases ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... cases • Sjögren syndrome ... polyangiitis without renal ... antibodies #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary Antinuclear ... & renal involvement ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... pancreas, biliary, renal ... autoantibodies (antinuclear ... antibodies, rheumatoid ... #rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis ... Scleromalacia perforans • Pulmonary ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... Symptoms #diagnosis #rheumatology
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Glucose/Temp • ACS ... Bradycardia • Renal ... Hyperkalemia Pulmonary ... fever • Chagas disease ... • Acute rheumatic
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... : • 10%-15% Pulmonary ... Distal (Type I) renal ... Adenocarcinoma Treatment ... #Rheumatology #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Inhibitors of Na+K+2Cl ... Torsemide) • Acute pulmonary ... Inhibitors of Renal ... Tolvaptan) • Treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and renal abnormalities ... • Cogan Syndrome ... Diagnosis: Systemic rheumatic ... • Urinalysis (Renal ... differential #diagnosis #rheumatology