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diagnosis causes algorithm treatment nephrology anemia oncology cardiology classification criticalcare dermatology hyponatremia lupus secondary signs sle symptoms systemic table workup
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... Algorithm #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology ... #differential
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... Neoplastic / Hematologic ... Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... thromboembolism, renal ... AIN) • Drugs (e.g ... #Diagnosis #nephrology
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
- Cirrhosis Syndrome ... - Malignancy (e.g ... CNS pathology (e.g ... hemorrhage) - Pulmonary ... pathology (e.g.
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... GI losses • Renal ... Uosm < 100 mmol/kg
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Hyponatremia - Differential ... Pain/Post-op • Neurologic ... • Drugs • Pulmonary ... GI losses • Renal ... Uosm < 100 mmol/kg
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Rare • Drugs (e.g ... ASA) • Renal Disease ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Thrombocytosis #Differential ... Diagnosis #Causes #hematology
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