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diagnosis hematology coagulation anticoagulation dic disseminated intravascular testing workup abnormal algorithm anticoagulants causes comparison diabetic differential disease dka doac effects
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
- Prolonged aPTT ... and Prolonged PT ... - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time (PT ... Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... #PTT #Prothrombin ... Thromboplastin #laboratory
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Testing #Diagnosis #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... venipuncture sites Laboratory ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
GI. uterine) Laboratory ... 2B) • Normal PT ... INR • Normal aPTT
Hypocalcemia Laboratory Evaluation Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory ... Serum levels of PTH ... #Hypocalcemia #Laboratory ... Hyperparathyroidism #Diagnosis #Endocrinology
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 ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... diagnosis #hematology #laboratory
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
PT and/or aPTT) ... pathophysiology #hematology #laboratory
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
sensitive - if pts ... HHS #comparison #laboratory ... #diagnosis #endocrinology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... be performed PT ... , PTT, and fibrinogen
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