16 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... or APTT Artifactually ... or APTT? ... to identify the cause ... of Prolonged APTT
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PTTProlonged ... PTTProlonged ... PTTProlonged ... PTT, Normal PT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... aPTT) 3. ... the aPTT alone ... PT and aPTT 1. ... #aPTT #Prolonged
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Clinical • Easy bruising ... bleeding • Prolonged ... 2B) • Normal PT ... INR • Normal aPTT ... (prolonged if very
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... PT and aPTT If ... aPTT are both prolonged ... Causes include : ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... #treatment #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/ABNORMAL PTT: ... Perform a PTT mixing ... prolonged after ... and the PTT suggests ... discern these causes
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... normal in mild cases
Graves Disease - Autoimmune Hyperthyroidism
Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50
Diagnosis: 
1 )
Epidemiology: Most common cause ... • Methimazole/PTU ... Hyperthyroidism #diagnosis #management ... #endocrinology
STAGES of CHF (A, B, C, D), however, describe the severity of structural abnormalities that impair
that may help prolong ... hospitalization arising ... flare ups that cause ... #Management #Cardiology