22 results
diagnosis differential rheumatology treatment causes disorders workup abnormal algorithm blood coagulation platelet product prolonged pt reactions activation aggregometry antinxp2 antinxp2dm
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
or APTT Artifactually ... Is a Systemic Disease ... or APTT? ... prolonged #diagnosis #hematology ... mixing #studies #PTT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... inhibitor • Liver disease ... Thromboplastin Time (PTT ... #PTT #Prothrombin ... Thromboplastin #laboratory #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... /aPTT normal • ... Differential #Diagnosis #Management ... #Algorithm #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
and/or aPTT Prolonged ... Early liver disease ... typically prolong aPTT ... and aPTT 1. ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... • Severe Liver Disease ... INR < 2.3 - APTT ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... 2B) • Normal PT ... INR • Normal aPTT ... VonWillebrand #Disease ... #Diagnosis #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... ) • aPTT is prolonged ... mixing study (aPTT ... #treatment #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
/NORMAL PTT: • ... /ABNORMAL PTT: ... Perform a PTT mixing ... and the PTT suggests ... Differential #Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
for decreased PLT ... , aPTT(liver disease ... bypass), LFT (liver disease ... or if a primary hematologic ... Causes #Workup #hematology
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Diagnosis and Management ... Activation: Liver disease ... , Kidney Disease ... Hypocalcemia #Diagnosis #Management ... #endocrinology
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