13 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
PT (INR), Prolonged ... PTTProlonged ... PT (INR), Prolonged ... PTTProlonged ... PTT, Normal PT
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Step 1: Is the PT ... Prolonging the PT ... to identify the cause ... of Prolonged APTT ... mixing #studies #PTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
PT and/or aPTT ... Time (PT) 1. ... PT and aPTT 1. ... #aPTT #Prolonged ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
PT and aPTT If ... the PT and the ... aPTT are both prolonged ... #Abnormal #PT ... #aPTT #Prolonged
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... PT/PTT • Low ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... < 2.3 - APTT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time (PT ... Thromboplastin Time (PTT ... Prothrombin Time (PT ... thematttsai #PT ... #PTT #Prothrombin
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding • Prolonged ... 2B) • Normal PT ... /INR • Normal ... aPTT (prolonged ... Disease #Diagnosis #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
/NORMAL PTT: • ... Perform a PTT mixing ... prolonged after ... PTT suggests liver ... discern these causes
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
platelet aggregation PT ... , aPTT: • Expected ... monitor using INR ... use PT D-dimer ... Scoring #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
in selected cases ... : INR/PT, aPTT(liver ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology