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diagnosis hematology differential causes coagulation workup criticalcare dic disorders disseminated intravascular laboratory management aggregometry aki algorithm anticoagulant anticoagulants apixaban bleeding
Markers of Organ Dysfunction in Severe Sepsis Altered consciousness Confusion Psychosis Tachycardia Hypotension Altered CVP Altered
Jaundice Enzymes, PT ... Creatinine PT ... /APTT, D-Dimer ... Platelets, Protein
Causes of AKI in Pregnancy - Differential Diagnosis Creatinine - Platelets - Transaminases - LDH - PT/PTT
Creatinine - Platelets ... Transaminases - LDH - PT ... /PTT - Schistocytes
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Anticoagulants #Tests #Anticoagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... /PTT • Low plasma ... Fibrinogen: ↓ • PT ... /INR: ↑ • PTT: ... INR < 2.3 - APTT
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Laboratory • Normal platelet ... 2B) • Normal PT ... INR • Normal aPTT
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... , PT, PTT (diff ... count and platelet ... • Platelet flow
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
multicomponent complexes on platelets ... Coagulation #Cascade #platelet ... thrombin #clot #PT ... #PTT #diagnosis ... pathophysiology #anticoagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
== NORMAL PT ... /NORMAL PTT: • ... level NORMAL PT ... Perform a PTT mixing ... /NORMAL PTT: Suggests
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
< 1800/uL, • platelet ... iron studies, PT ... /aPTT Differential
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Coagulation (DIC) Platelet ... thrormbin-induced platelet ... aggregation PT ... , aPTT: • Expected ... using INR use PT
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