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management differential algorithm antiphospholipid dermatology oncology anticoagulation aps classification criteria disease guidelines hepatology hepatopulmonary sweet thrombocytopenia thrombosis vasculitis workup abdominal
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... Venous Thrombosis - Arterial ... Antiphospholipid #Syndrome ... EULAR2019 #guidelines #rheumatology ... #hematology #treatment
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... Fat Emboli ARTERIAL ... • Cardiac: - Atrial ... thrombus - atrial ... pathophysiology #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL-1B, ATRA ... #Algorithm #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
calculators - HAS-BLED (atrial ... validated for VTE treatment ... prophylaxis and atrial ... Anticoagulation #Factors #Hematology ... #Diagnosis
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Anticardiolipin antibodies (aCL ... confirmed venous, arterial ... to be present Treatment ... patient has an arterial
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
anti-synthetase syndrome ... at diagnosis). ... after 2 years of treatment ... Autoimmune #Myositis #diagnosis ... #rheumatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Summary A defect in arterial ... cycles after right atrial ... passage • Arterial ... #treatment #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... treatment Pathophysiology ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - ... arterioles - Treatment ... David #Susac #Syndrome ... #Diagnosis #Management ... #Rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... Criteria for Behget's Syndrome ... venous thromboses, arterial ... #criteria #rheumatology
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