12 results
Massive Hemoptysis - Diagnosis and Management
 • Definitions: 
   - Hemoptysis = bleeding from
Massive Hemoptysis ... Definitions: - Hemoptysis ... cords - Pseudo-hemoptysis ... cause death by asphyxia ... Diagnosis #Management #treatment
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Cold Autoimmune Hemolytic ... Spherocytes • Treatment ... Mostly transient hemolysis ... • Treatment: Warm ... #Anemia #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... defects. 1) HELLP (Hemolysis ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA #Treatment ... #management #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... Gilbert's syndrome • Hemolysis ... #differential #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
HELLP Syndrome (Hemolysis ... clinical features: Hemolysis ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... diagnosis #icp #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Gilbert's syndrome • Hemolysis ... Bilirubin: RBC (hemolysis ... LDH: Heart, RBC (hemolysis ... ) • ALP: Bone, ... diagnosis #algorithm #hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Post-partum, ICH/TBI, Hemoptysis ... #Indications #Pharmacology ... #hematology
Nebulized Tranexamic Acid for acute treatment of stable hemoptysis 

- Mike O'Brien
@MikeEMPharmD

#Pharmacology #EBM #Management #Dosing #Pathophys
Acid for acute treatment ... of stable hemoptysis ... MikeEMPharmD #Pharmacology ... TranexamicAcid #Hemoptysis