14 results
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... and Differential ... - Hemolytic # ... Anemia #Workup # ... #causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Polychromatic Macrocytes ... Bleed • Hemolysis ... #Differential #
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... #Hemolytic #Anemia
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... hemolytic anemia ... hemolytic anemia ... #Morphology #differential ... hematology #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... Lead poisoning • Macrocytic ... spherocytosis, Hemolytic ... key #diagnosis #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... RBCs, DAT (-) → ... idiopathic, malignancy, autoimmune ... #Anemia #Differential ... Diagnosis #Algorithm #causes
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... , CKD • Hemolytic ... Spherocytosis, G6PD, PK, HbC ... - Extrinsic: Autoimmune ... Infections Macrocytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... • Intrinsic RBC ... Extravascular #Causes ... #differential #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... anemia
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... Hemorrhage or hemolysis ... the most likely cause ... recovery also causes