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diagnosis differential symptoms management algorithm hematology classification pathophysiology syndrome cobalamin nephrology abnormal celiac cord dementia disorders elevation gastroenterology hepatology korsakoff
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... (>100 fL) • B12 ... Deficiency • ... Folate Deficiency ... Diagnosis #Algorithm #Causes
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... : SIBO, Celiac disease ... Stomach: Pernicious anemia ... #Deficiency #Cobalamin
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... • Pancreatic Disease ... and Folate Deficiency ... • Liver Disease
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Vitamins and Vitamin Deficiency ... gestation • Vitamin B12 ... #Vitamins #Deficiency ... differential #diagnosis #signs
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... Megaloblastic: Vitamin B12 ... deficiency • ... Alcohol use, Liver disease ... differential #diagnosis #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... of Chronic Disease ... Diagnosis #Algorithm #Causes
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... Autoimmune - Pernicious anaemia ... , coeliac disease
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... • Iron-deficiency ... anemia unresponsive ... without discernable cause ... • Signs of osteoporosis
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... turnover • Iron, B-12 ... , or folate deficiency ... • Hemolytic anemia ... End-stage renal disease
Causes of Dementia / Cognitive Impairment - Differential Diagnosis Algorithm Affecting Multiple Domains • Depression • Delirium Decline
Causes of Dementia ... Subdural Hematoma • B12 ... deficiency • ... • Parkinson's Disease ... CognitiveImpairment #Dementia #Neurology
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