27 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... anemia - Anemia ... disease - Vitamin B12 ... Underproduction #Algorithm #hematology ... #differential #workup
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... Deficiency • ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology ... #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... kidney disease, Acute ... blood loss, Anemia ... Megaloblastic: Vitamin B12 ... diagnosis #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... • B12/Folate ... AnemiaAnemia ... Non-lmmune #Anemia
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
particular degree of anemia ... Index < 2: • Anemia ... loss), Vitamin B12 ... Index > 3: • Acute ... Production #Index #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... • Nonmalignant hematologic ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... High in acute blood ... (EPO), iron or B12 ... for degree of anemia ... thecurbsiders podcast #Anemia
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Encephalopathy - Acute ... Thiamine (B1) Deficiency ... Clinical Diagnosis ... #Deficiency #diagnosis ... #criteria #neurology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Nutritional: DiabetesB12 deficiency ... , Uremia/ESRD, Hypothyroidism ... Fabry's disease, Acute ... diagnosis #causes #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... Clinical Presentation ... #oncology #hematology