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differential management algorithm signs testing ana antinuclear arthritis cytoplasmic disease disorders patterns symptoms syndrome thrombocytopenia antinxp2 antinxp2dm antiphospholipid apls arteritis
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Nutritional: B12 ... DIC, TTP, HUS - Antibody-mediated ... #Framework #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... (CVID, WAS), (neurologic ... #Causes #Workup ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... , OJ, PL-7, PL-12 ... body-like: - Neurologic ... #differential #diagnosis ... #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Check Vitamin B12 ... glycoprotein (MOG) antibody ... Deficiency: - Vitamin B12 ... #management #neurology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... maternal chromosomal causes ... Hypercoagulable #Workup ... #Algorithm #diagnosis ... #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... , OJ, PL-7, PL-12 ... body-like: • Neurologic ... #differential #diagnosis ... #rheumatology
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