14 results
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... of Monoclonal Gammopathy ... Cold agglutinin disease ... manifestations #dermatology ... #skin #clinical
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
frequently mistaken for cellulitis ... Goldberg, M.D. - UCSD ... Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... nemaline myopathy Cutaneous-centered ... Ig deposition disease ... #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... malignancy (CLL) - Monoclonal ... Viral Infection Clinical ... presentation) • Cutaneous ... hemolytic #anemia #hematology
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
Diagnosis is clinical ... No treatment is ... one-time dose of 12 ... migrans #skinRash #dermatology ... #clinical #photo
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... vasculitis) • Cutaneous ... oral ulcers in 12 ... Arthritis, AS Treatment ... : monoclonal TNF-aIpha
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... transformation) Treatment ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... Leukemia #oncology #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
antibody - Early treatment ... vaccinations Renal disease ... deposition disease ... rituximab (in clinical ... Complications #diagnosis #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... dermatitis - Cellulitis ... Treatment: - Systemic ... Syndrome #diagnosis #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... involvement (2%) Cutaneous ... • Severe Liver Disease ... + Bleeding Treatment ... #management #hematology