110 results
diagnosis rheumatology dermatology syndrome algorithm neurology hepatology infectiousdiseases classification gastroenterology hemophagocytic idsa lymphohistiocytosis oncology radiology summary arthritis blood chagas fungal
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... erythematosus • HLH ... consumption • Vitamin B12 ... deficiency Infections ... #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • B12 ... Alloimmune • anti-HLA ... Vasculitis • Infection ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Demyelinating Diseases - Differential Diagnosis • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE •
- Differential ... Inflammatory: MS ... nodosa, SLE • Infectious ... Other: Vitamin B12 ... Diagnosis #causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Inflammation, Chronic Infection ... (>100 fL) • B12 ... #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Framework Non-Infectious ... , Sarcoidosis, HLA-B27 ... rare), Idiopathic Infectious ... #Diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
associated with infection ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Conditions Associated With Hyperferritinemia DDx of extreme hyperferritinemia >10,000 Not just HLH - in fact, most common
fact, most common causes ... Liver disease 3. ... - Malignancy—Hematologic ... Hyperferritinemia #differential ... #diagnosis #causes
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