59 results
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... - Malignancy: Leukemia ... Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... MINTC #Mnemonic #dermatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Wiskott-Aldrich syndrome ... Cancer: • Leukemia ... consumption • Vitamin B12 ... deficiency Infections ... Differential #Diagnosis #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... transformation to acute leukemia ... only curative treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Leukemia, Tumour ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... appearing during the disease ... Infectious manifestations ... differential #diagnosis #dermatology ... #oncology #clinical
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... microglobulin Treatment ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection Malar ... infection • Lyme ... disease • Rosacea ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology