105 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... thickening Signs and Symptoms ... interstitial lung disease ... Scleroderma #SSc #rheumatology ... diagnosis #signs #symptoms
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... Skin manifestations ... : • Systemic steroids ... #pharmacology #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Arthralgia/arthritis, Skin ... solid cancers • Systemic ... diagnosis #management #treatment ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... • MCTD (SLE/systemic ... Treatment: • ... Summary #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Eosinophilia and Systemic ... Symptoms (DRESS ... ) Syndrome Treatment ... , IVIG etc • Skin ... #Management #dermatology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
ulceration of the skin ... a number of systemic ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Raised off of the skin ... Drug #Reactions #dermatology ... #clinical #comparison ... #classification
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Systolic dysfunction ... multifactorial mechanisms Hematologic ... disorders, lenectomy Systemic ... Hypertension #PHTN #Classification
Chronic Obstructive Pulmonary Disease (COPD)
 • COPD Definition
 • Role of PFTs
 • COPD Classification and
Obstructive Pulmonary Disease ... PFTs • COPD Classification ... - Evaluate symptoms ... risk in the last 12 ... management #GOLD2022 #treatment