56 results
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... Joint #Disorders #msk
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... (SLE) General: ... Sjögrens (15%) Skin ... pain (20%) Renal disease ... #signs #symptoms
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... - Neurological 12% ... #Systemic #Lupus ... autoantibodies #signs #symptoms ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Evolution: Chronic disease ... #lupus #Systemic
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Arthralgia/arthritis, Skin ... fraction < 20% Differential ... solid cancers • Systemic ... diagnosis #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... oral ulcers in 12 ... ) Differential Diagnosis ... Oral aphthae : SLE ... Arthritis, AS Treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... • Treatment: ... months to years) Systemic ... Evolution: Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... ) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... Symptoms (DRESS ... Symptoms: • The ... Resolution > 15 days Differentials ... : symptomatic treatment