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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Skin Findings: ... : • Behcet Disease ... #Vasculitis #skin ... #dermatology #rheumatology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Dermatological semiology of Cutaneous ... the context of cutaneous ... Connective tissue disease ... #dermatology #semiology ... lesions #diagnosis #clinical
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Human parvovirus B19 ... Human parvovirus B19 ... infection • Lyme disease ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome • Vasculitis
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... leukocytoclastic vasculitis ... #oncology #clinical ... #skin
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Skin, glomeruli ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... Rarely dominate the clinical ... Granulomatous vasculitis ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... Cold agglutinin disease ... monoclonal #gammopathy #Cutaneous ... manifestations #dermatology ... #skin #clinical
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
Clinical manifestations ... - Skin involvement ... neuropathy Treatment ... with refractory disease ... #Rheumatology #
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
to hours into treatment ... Raised off of the skin ... Blistering and/or skin ... Drug #Reactions #dermatology ... #clinical #comparison
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ) • Cutaneous Lesions ... Behcet syndrome (Clinical ... oral ulcers in 12 ... Arthritis, AS Treatment