35 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
- Anemia of chronic ... kidney disease ... - Vitamin B12 and ... Underproduction #Algorithm #hematology ... #differential #workup
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... - Wilson disease ... heart failure (chronic ... #Differential #Hepatology ... #Cirrhosis #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Anemia of Chronic ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... underlying liver disease ... #Hepatology #gastroenterology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... • Infections: Chronic ... Diagnosis #Algorithm #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, ... Megaloblastic: Vitamin B12 ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Deficiency • B12 ... Disease • Marrow ... Diagnosis #Algorithm #Causes ... #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Disorders: • Chronic ... Colitis and Crohn’s Disease ... Chickenpox Other Causes ... Irradiation • Cirrhosis ... #hematology #basophils
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... intralobular bile ducts causes ... cholestasis → Cirrhosis ... cholangitis #diagnosis #workup ... #hepatology