56 results
diagnosis differential management anemia algorithm oncology syndrome thrombocytopenia hemolytic hemophagocytic lymphohistiocytosis classification mcv pancytopenia reactions aflp aiha blood cirrhosis coagulation
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • B12 ... methotrexate) • Drugs Autoimmune ... • anti-HLA antibodies ... #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... Inflammatory and Autoimmune ... erythematosus • HLH ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Differential Diagnosis Table ... Cold Agglutinin Disease ... MatthewHoMD #Autoimmune ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Autoimmune Mediated ... and Screen for HLH ... HLH syndrome 5. ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... with infection or autoimmune ... disease, treatment ... for refractory disease ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Autoimmune Mediated ... and Screen for HLH ... HLH syndrome 5 ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Advanced Liver Disease ... - Malignancy, Autoimmune ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
solid cancers • Autoimmune ... diseases: SLE++ ... Adult-onset Still disease ... Treatment: • ... #summary #rheumatology
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