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diagnosis differential management algorithm leukemia causes chronic cll lymphocytic acute aki aplastic approach biliary calculation encephalopathy gap globulin grading hemeonc
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... (>100 fL) • B12 ... #MCV #Classification ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... Disease • Marrow ... #Classification ... Algorithm #Causes #Hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
LC deposition disease ... • Hematologic ... malignancies Treatment ... #Oncology #Differential ... #Diagnosis #Classification
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Index < 2: • Anemia ... loss), Vitamin B12 ... Chronic kidney disease ... infiltration (e.g. cancer ... Production #Index #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - ... PRODUCTION • Vitamin B12 ... Peptic ulcer disease ... #Cirrhosis #Differential ... #Diagnosis #Hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... chemotherapy for low-risk disease ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology
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