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diagnosis differential management algorithm anemia classification syndrome cirrhosis dermatology rheumatology gastroenterology leukemia macrocytic mcv biliary blood chronic cll disorders druginduced
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... cold agglutin disease ... e.g. sickle cell disease ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Macrocytic Anemia • 812 ... Hypothyroid • Liver Disease ... diagnosis #algorithm #hematology ... #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell disease ... , Hemoglobin H disease ... Diagnosis #Algorithm #workup ... #hematology #testing
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... esp if severe disease ... #Anemia #AIHA #Treatment ... #management #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Serum Sickness Hemolytic ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
chronic kidney disease ... - Vitamin B12 ... Underproduction #Algorithm #hematology ... #differential #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
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