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diagnosis differential causes liver oncology classification gastroenterology rheumatology cirrhosis hepatitis injury macrocytic mcv summary syndrome autoimmune cll druginduced hemolytic leukemia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
- Anemia of chronic ... disease - Vitamin ... B12 and/or folate ... #hematology #diagnosis ... #differential #workup
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Hypothyroid • Liver Disease ... #Macrocytic #Anemia ... differential #diagnosis #algorithm ... #hematology #workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... of Chronic Disease ... of Chronic Disease ... (>100 fL) • B12 ... #Causes #Hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... symptoms of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
: • Acute or Chronic ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Deficiency • B12 ... • Anemia of Chronic ... Disease • Marrow ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... • Infections: Chronic ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... e.g. ascites), Chronic ... #hepatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Macrocytic RBC: Vitamin B12 ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... differential #diagnosis #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... underlying liver disease ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
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