15 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... , Acute hemolysis ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Macrocytic RBC: Vitamin B12 ... , McLeod blood group ... Microangiopathic Hemolytic ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Transfusion reactions ... , Drugs, Liver Disease ... - Peripheral Blood ... Differential #Diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Graft Versus Host Disease ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... evaluation or workup ... allergy, drug reaction ... glucocorticoid treatment ... Differential #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
loss), Vitamin B12 ... Chronic kidney disease ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Hemolysis on labs ... Graft Versus Host Disease ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... diagnosis #management #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
High in acute blood ... loss, hemolysis ... (EPO), iron or B12 ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... hemorrhage and hemolysis ... of Peripheral blood ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology