33 results
diagnosis differential anemia algorithm management causes comparison classification oncology allergy atlas cirrhosis disorders hemolysis hepatitis hypersensitivity microscopy morphology pathophysiology product
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Other: Transfusion reaction ... ) (e.g. lupus, CLL ... cold agglutin disease ... - Transfusion reaction ... differential #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... , Acute hemolysis ... Diagnosis #Algorithm #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Macrocytic RBC: Vitamin B12 ... , McLeod blood group ... Microangiopathic Hemolytic ... differential #diagnosis #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... cells: Sickle cell ... disease Bite cells ... Smear #Analysis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Transfusion reactions ... Defects: Sickle cell ... - Peripheral Blood ... Differential #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... disease (diverse ... Diagnosis #Algorithm #workup ... #hematology #testing
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
loss), Vitamin B12 ... Chronic kidney disease ... Microangiopathic hemolytic ... defects (e.g. sickle cell ... Production #Index #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
the total white blood ... during an allergic reaction ... Or Inflammatory Reactions ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... malignancies -> CLL ... significance (MGUS), CLL ... sensitize red blood ... #hematology #diagnosis
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Graft Versus Host Disease ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... diagnosis #management #hematology
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