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management differential erythematosus hematology systemic syndrome thrombocytopenia druginduced summary vasculitis acidosis activation acute algorithm cerebritis cns comparison cryoglobulinemia cryoglobulins cutaneous
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... Discontinuation of causal ... #table #rheumatology ... #diagnosis #management
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Lupus Classification ... (SCLE-DIL) - ... #Classification ... erythematosus #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... versus DIL • ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • B12 ... Autoimmune • ITP • SLE ... • TTP/HUS • DIC ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... permeability Diagnosis ... Erythematosus #SLE ... CNS #neurology #rheumatology
Cutaneous Lupus Erythematosus • Acute Cutaneous Lupus (ACLE) • Neutrophilic Dermatoses • Vascular Lesions •
Cutaneous Lupus ... (SCLE) • Intermittent ... Erythematosus #diagnosis ... #types #venn #rheumatology ... #classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... 0.5-0.7 g/g by 12 ... months Classification ... Nephritis #Management #treatment ... #management #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... #types #classification ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Nutritional: B12 ... Microangiopathy: DIC ... - Autoimmune: SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I ... #Rheumatology
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