33 results
diagnosis differential rheumatology causes management erythematosus oncology sle classification fever hepatology macrocytic signs symptoms systemic workup activation acute aiha allergic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... Microangiopathic hemolytic ... purpura (TTP), Hemolytic ... usually IgG) (e.g. lupus
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... crisis • Severe B12 ... • Mechanical hemolysis ... anemia" • HELLP ... #hemolysis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... , CKD • Hemolytic ... Folate deficiency, B12 ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... purpura/hemolytic ... uremic syndrome ... , Hematology 2012 ... #Differential #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... • Bleeding • Hemolysis ... (>100 fL) • B12 ... #MCV #Classification ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... Antibody-mediated hemolysis ... consumption • Vitamin B12
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Schistocytes, thrombocytopenia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #workup #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
NEUROLOGIC - HEMOLYTIC ... ANEMIA - LEUKOPENIA ... (<1000/MM3) - THROMBOCYTOPENIA ... the absence of hemolytic ... #Rheumatology #
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
PRODUCTION • Vitamin B12 ... splenomegaly, Thrombocytopenia ... Destruction: Zieve's syndrome ... , Autoimmune hemolytic ... anemia, Hemolysis
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