18 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Megakaryopoiesis • B12 ... Non-lmmune: • HELLP Syndrome ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... #hematology #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... (AKI) in Patients ... change disease • Hematologic ... malignancies Treatment ... Classification #Nephrology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... #hematology #secondary
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach to Acute ... e.g AEIOU ) or anuria ... require urgent nephrology ... creatinine (in 12 ... workup #diagnosis #nephrology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, Acute ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Parvovirus B19 ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... • Sezary syndrome ... workup #oncology #hematology