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diagnosis differential management algorithm causes rheumatology neurology cancer deficiency leukemia lupus acute b1 chronic cirrhosis cll comparison dermatology encephalopathy erythematosus
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... Differential #Diagnosis #Classification ... #Nephrology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... (>100 fL) • B12 ... #MCV #Classification ... Algorithm #Causes #Hematology
Gastric Neuroendocrine Tumor (NET) Types Type 1 - Chronic atrophic gastritis and pernicious anaemia Type 2 - Zollinger
and pernicious anaemia ... Zollinger Ellison syndrome ... Tumor #NET #Types #Classification ... #oncology #comparison
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Deficiency • B12 ... • Anemia of Chronic ... #Classification ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Low Serum B12 ... - Low Serum B12 ... Myelodysplastic Syndromes ... • Rule out B12 ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... - Parvovirus B19 ... • Parvovirus B19 ... Treatment: ... #oncology #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolytic-uremic syndrome ... crisis • Severe B12 ... macroangiopathic hemolytic anemia ... " • HELLP syndrome ... differential #diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... Megaloblastic: Vitamin B12 ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
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