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management syndrome differential algorithm causes rheumatology anemia leukemia photo workup activetb aplastic chronic classification cll comparison disease disorders gammopathy hodgkins
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... : B-symptoms, bruising ... /bleeding, fatigue ... predominant immature cells ... #Algorithm #hematology
Diagnostic criteria for Neutropenic Enterocolitis (NEC) Major Criteria: • Neutropenia (ANC <500 x 10^9 cells/L) • Bowel
Diagnostic criteria ... ANC <500 x 10^9 cells ... Diarrhea • Lower Gl bleeding ... #criteria #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... = funny-shaped cells ... only curative treatment ... #Management #treatment ... #hematology #oncology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... disorder Clinical ... factor VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... validated for VTE treatment ... studies suggest net clinical ... Anticoagulation #Factors #Hematology ... #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Leukemia - History of Bleeding ... Reed-Sternberg Cells ... Algorithm #Causes #Hematology ... #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... #management #treatment ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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