35 results
Von Willebrand Disease - Clinical Presentation, Diagnosis and Management

- Dr. Eric Strong @DrEricStrong - Strong Medicine
Von Willebrand Disease ... - Clinical Presentation ... Diagnosis and Management ... VonWillebrand #Disease ... #hematology #treatment
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... disorder Clinical ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... Chronic Management ... #treatment #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Hepatosplenomegaly, cytopenias(bleeding ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... inflammation, leading ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Severe Liver Disease ... Treatment: ... diagnosis #causes #treatment ... #management #hematology