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hepatology transaminitis causes function hepatitis interpretation tests anemia bruising chemistry classification drug elevated enzymes gastroenterology hepatocellular idiosyncratic induced laboratory liverenzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... Chronic - ongoing ↑ LFTs ... #differential # ... gastroenterology #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... (>1000): • DILI ... injury) • Ischemic ... Diagnosis #hepatology
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal ... liver tests in ... Hepatocellular Pattern #LFTs ... #diagnosis #differential ... #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... • Iatrogenic: DILI ... function may be abnormal ... RBC (hemolysis, bleeding ... diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... hepatocellular injury ... Function #Tests #LFTs ... Interpretation #diagnosis ... #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Diagnosis #Algorithm ... #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Burak @kwburak #LFTs ... #diagnosis #hepatology
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