21 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... - Differential ... • Autoimmune hepatitis ... #Differential # ... Diagnosis #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... #Diagnosis #hepatology ... #transaminitis
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Acute Viral Hepatitis ... , Toxic Hepatitis ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... cirrhosis or chronic hepatitis ... Chylous <1% #Ascites ... #Differential # ... Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Liver Injury - Differential ... • Infections: Hepatitis ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... Tuberculosis • Hepatitis ... Leukemia - History of Bleeding ... Pancytopenia, WBC differential ... Algorithm #Causes #Hematology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... - Alcoholic hepatitis ... - Bile ascites ... Causes #diagnosis #differential ... #hepatology #SAAG
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... portal HTN: • Ascites ... Cirrhosis/acute hepatitis ... Diagnosis #causes #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... Hepatobiliary #hepatology ... #hepatitis #differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... disorder (e.g. ascites ... ), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology