49 results
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... #AFib #Diagnosis ... #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
clinical benefit of anticoagulation ... of withholding anticoagulation ... #Calculators #Anticoagulation ... #Factors #Hematology ... #Diagnosis
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
- Differential Diagnosis ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... #Algorithm #gastroenterology ... #hepatology
Stroke and bleeding risk stratification with the CHADS2-VASc and HAS-BLED schemas

#Diagnosis #Hematology #CHADS2 #CHADS2VASc #HASBLED #Comparison
Stroke and bleeding ... HAS-BLED schemas #Diagnosis ... #Hematology #CHADS2 ... Stroke #Bleed #Anticoagulation
HAS-BLED Score - Risk of Major Bleeding in 1 Year
Characteristics (1 point each)
 • Hypertension: Baseline
Risk of Major Bleeding ... transplant • Liver ... Cirrhosis, or total bilirubin ... #anticoagulation ... #diagnosis #stratification
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... - Acquired • Anticoagulation ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
HAS-BLED Score
 - Hypertension: Baseline SBP > 160mmHg
 - Renal disease: Cr > 2.6mg/dL, on HD,
transplant - Liver ... Cirrhosis, or total bilirubin ... History of major bleeding ... #Risk #Score #Bleeding ... #Anticoagulation
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
in bone Total bilirubin ... TBili) Direct bilirubin ... Indirect bilirubin ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... Elevation: • Bilirubin ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential #Hepatology