27 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
non-ICU vs ICU causes ... MRCP, ERCP, liver ... Hyperbilirubinemia #direct #bilirubin ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... #Workup #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... , Thrombosis, Emboli ... week • Direct bilirubin ... RBC (hemolysis, bleeding ... diagnosis #algorithm #hepatology
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Stabilization Concern for Liver ... Consult GI ± EGD Causes ... Disease • Variceal Bleeding ... GAVE (idiopathic, liver ... gastrointestinal #gastroenterology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Iatrogenic) • Liver ... Coagulation #Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatocellular injury • Bilirubin ... week • Direct bilirubin ... Elevation: • Bilirubin ... RBC (hemolysis, bleeding ... #differential #Hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Syndrome, Ischemic Liver ... valves (septic emboli ... considered in all cases ... coagulation and other causes ... pathophysiology #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... Reticulocytosis • Liver ... #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of hemolysis or liver ... associated with bilirubin ... and stress may cause ... #hepatology #diagnosis ... #gastroenterology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
Abnormal renal/liver ... >2.3mg/dL) 1 Liver ... (cirrhosis, bilirubin ... S Stroke 1 B Bleeding ... AFib #Diagnosis #Hematology