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diagnosis rheumatology differential classification management activation ana anca antibodies antibody antineutrophil antinuclear aortitis cerebritis clues cns cryoglobulinemia cryoglobulins diseases hemostasis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... autoantibodies that will cause ... inflammation, leading ... #rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ANCA associated vasculitis ... (RA), Systemic lupus ... erythematosus ( ... SLE), Sarcoidosis
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle ... #erythematosus # ... rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... in drug-induced SLE ... ANCA-Associated Vasculitis ... Renal-limited vasculitis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... manifestations: from easy bruising ... purpura to mucosal bleeding ... erythematosus [ ... SLE], AOSD) • Infection
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... erythematosus (
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... , and SLE) • Urinalysis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... (systemic lupus ... erythematosus) ... infections - Vasculitis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... discern these causes ... integrity == • Vasculitis ... Differential #Diagnosis #Hematology
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