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management differential oncology causes algorithm anticoagulation mds myelodysplastic syndrome workup activation atopic atopy b12 calculation calculators cancer chronic classification cll
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Treatment: • Consider ... #Anemia #diagnosis ... #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
) and IMPROVE (VTE ... validated for VTE ... treatment, only ... Anticoagulation #Factors ... #Hematology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... supportive care (growth factors ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... anemia Treatment ... #hematology #diagnosis
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... Classify severity Treatment ... by a hemophilia treatment ... #Management #treatment ... #hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... prolonged if very low factor ... VIII) Treatment ... VonWillebrand #Disease #Diagnosis ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
) / Maturation Factor ... The maturation factor ... marrow failure: Aplastic ... Production #Index #hematology ... #diagnosis #calculation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... Treatment: ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... SOAP) - Risks factor ... changes), high MCV anemia ... Causes #Workup #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... • Aplastic Anemia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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