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diagnosis management differential algorithm oncology anemia syndrome classification dermatology gastroenterology reactions bruising coagulation eosinophilia hepatitis hepatopulmonary injury leukemia liver medications
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... Normal PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Hematology #coagulation ... #disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... or if a primary hematologic ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... Coagulation #Bleeding ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Peripheral blood ... for secondary causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Treatment: ... Treat primary cause ... #treatment #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... inflammation, leading ... thrombosis and/or blood-brain
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Classify severity Treatment ... by a hemophilia treatment ... Diagnosis #Management #treatment ... #hematology
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