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diagnosis differential management cardiology rheumatology lupus comparison erythematosus clinical criticalcare endocarditis nephrology types vasculitis allergy chronic dermatology hematology hypersensitivity infectiousdiseases
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Constitutional domain: Fever ... anticoagulant • Complement ... #Criteria #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... months to years) Systemic ... 80% - Low complement ... #comparison #table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... Anaphylaxis, Hay fever ... glomerulonephritis, Systemic ... #classification
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Positive in 60-80% of cases ... 80% - Low complement ... #lupus #Systemic
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... , seasonal hay fever ... Complement activation ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... infections include systemic ... See below for table ... helpful paper complements ... #Differential #Table
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
Causes of Fever ... Differential Diagnosis Algorithm ... Autoimmune: • SLE ... Differential #Diagnosis #Algorithm ... #causes
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Systolic Murmurs ... Differential Diagnosis Algorithm ... Carcinoid #Systolic ... Differential #Diagnosis #Algorithm ... #causes
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Exercise • Fever ... (MPA) • SLE ... Differential #Diagnosis #Algorithm ... #Causes
Primary and Secondary Causes of Mitral Regurgitation Primary (organic) chronic mitral regurgitation: • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... Leaflet: Rheumatic fever ... cushion defects), Systemic ... inflammation (SLE ... diagnosis #cardiology #causes
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