11 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Renal Disease, Liver ... Inflammation, Chronic Infection ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Macroangiopathic, Infections ... Non-megaloblastic: Liver ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury Differential ... Diagnosis: • Infections ... #Diagnosis #hepatology ... Transaminitis #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 10-20x normal - Infection ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... Extrinsic Causes: • Liver ... drug induced • Infections ... classification #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects, Drugs, Liver ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... changes), high MCV anemia ... gastric bypass), LFT ... (liver disease) ... Causes #Workup #hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Alcoholic Hep, Drugs, Infection ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... SLE) - Viral infections ... deficiency • Liver ... #Diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Include: • Viral infections ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology