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differential hepatology systemic symptoms algorithm autoantibodies erythematosus lupus sle workup antibodies autoimmune dermatology dermatomyositis management myositis pbc primary sclerosis vasculitis
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... quadrant discomfort Signs ... #Cirrhosis #Diagnosis ... #Algorithm #hepatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
ulcers, Primary Biliary ... Cirrhosis Anti-RNA ... Autoantibodies #diagnosis ... #rheumatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... significant portal HTN Signs ... pregnancy • Primary biliary ... #Differential #Diagnosis ... #causes #hepatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... , Shaw sign, holster ... sign, and Gottron's ... #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... failure PBC Signs ... #Cirrhosis #PBC ... #workup #hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... Associations #diseases #diagnosis ... #table #rheumatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... dullness, puddle sign ... incisional). 3) Signs ... concentration (bowel or biliary ... #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... : PBC (primary biliary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Erythematosus - Diagnosis ... 69% - Malar rash ... Differential Diagnosis ... autoantibodies #signs ... #differential #rheumatology
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