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diagnosis differential hematology anemia workup aiha causes disease glomerular hemolysis management nephrology nephrotic rheumatology agglutinin ags allergy alphagal anemias antiglobulin
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... blood smear + DAT ... Heinz bodies, DAT ... idiopathic, malignancy, autoimmune ... Differential #Diagnosis #Algorithm
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... • DAT Poly ( ... BrighamChiefs #direct ... #Autoimmune #Hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... • ↑ LDH • ↑ Indirect ... : • Autoimmune ... (AIHAs) • Alloimmune ... Differential #Diagnosis #Algorithm
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... would be autoimmune ... already listed) and alloimmune ... #Classification ... Diagnosis #Causes #Algorithm
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... IgG mediated - DAT ... IgM mediated - DAT ... BrighamMedRes #AIHA #Autoimmune ... #Hemolytic #Anemia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Mixed-type AIHA (7-8%) DAT-negative ... MatthewHoMD #Autoimmune ... #Hemolytic #Anemia
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
and Management Algorithm ... function panel, Direct ... LDH • ↑ Total/indirect ... aPTT normal • DAT ... Diagnosis #Management #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... elliptocytosis, autoimmune ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Positive Coombs testing ... post infectious setting ... CLL (older) • Autoimmune ... blood cells (RBCs) at
Alpha-gal Syndrome (AGS) - Diagnosis Algorithm Does patient have recurrent episodes of urticaria, angioedema or isolated GI
AGS) - Diagnosis Algorithm ... then consider testing ... Persistent irritation at ... - High fat ... AGS #Diagnosis #Algorithm
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