18 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... cyclophosphamide) #Acute ... Classification #Nephrology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... infections, TB, Acute ... Severe trauma, Acute
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Rituximab Evolution ... Acute phase ... arterioles - Treatment ... Diagnosis #Management #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... diagnosis #management #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... (Acute Febrile ... Excellent response to treatment ... #Acute #Febrile ... Criteria #Diagnosis #Hematology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
orbital pain, (Sub)acute ... OCBs (30-70%) • Evolution ... corticosteroids TREATMENT ... Diagnosis #Management #treatment ... #rheumatology #
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
exam and imaging Treatment ... ideally limit for acute ... Leflunomide (LEF) • JAKi ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology