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diagnosis differential hematology management rheumatology oncology sle classification erythematosus leukemia systemic thrombocytosis approach arthritis cll comparison damage dermatology diarrhea diseases
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... , Target Cells ... Inflammation • Cancer
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
Diagnosis and Evaluation ... Identification of onset (acute ... vs. chronic) 2) ... , liver, renal disease ... #Ddxof
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... • Infections: Chronic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... management of SLE • Evolution ... : Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis Algorithm ... Pulmonary Langerhans cell ... Arthritis, Systemic Lupus ... , Beomycin • Acute ... or Chronic Radiation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... extramedullary disease ... -> AML: Blast crises ... - infiltrates (anemia ... lymphoid organs When Cancer
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the ... Evaluation of Chronic ... Causes of acute ... Systemic disease ... #workup #diagnosis
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